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Objective:To improve the understanding of chronic lymphoblastic leukemia (CLL) with t(14;18)(q32;q21).Methods:The clinical data of 3 cases diagnosed as CLL with t(14;18)(q32;q21) in the Tianjin KingMed Medical Laboratory from January 2020 to January 2021 were retrospectively analyzed. The clinicopathological data, morphological examination, immunophenotype, cytogenetics and somatic mutation of immunoglobulin heavy chain variable region genes of patients were comprehensively analyzed, and the literature was reviewed.Results:All the 3 patients showed lymphatic proliferative diseases, and their morphological characteristics and immunophenotype were typical characteristics of CLL.Conclusions:The diagnosis of CLL is mainly based on the typical morphology and immunophenotype of tumor cells. The presence of t(14;18) should not be used to exclude the diagnosis of CLL.
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Objective To investigate the effect of resilience on fear of cancer recurrence in breast cancer patients and to find the specific role of perceived social support between them. Methods From April 2018 to January 2019, we invited 456 breast cancer patients hospitalized in the Department of Breast surgery in Qilu Hospital of Shandong University in Jinan to participate in the study and to finish a questionnaire survey which including the general information questionnaire, Chinese version of the Fear of Progression Questionnaire-Short Form, The Connor-Davidson Resilience Scale and Perceived Social Support Scale. Results The average score of fear of cancer recurrence in breast cancer patients was (41.5 ± 7.7), and 85.99%(313/364)of the patients′ score was clinically significant (total score ≥ 34). Resilience could negatively predict the fear of cancer recurrence (β=-0.240 P<0.01). Perceived social support is the moderation between resilience and fear of cancer recurrence (β =-0.179, P＜0.01). Conclusions The level of resilience could affect the level of fear of cancer recurrence in breast cancer patients, and the increase in the level of perceived social support could enhance the effect of resilience on the fear of cancer recurrence, thus further reducing the level of patient′s fear of recurrence.
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Objective@#To investigate the effect of resilience on fear of cancer recurrence in breast cancer patients and to find the specific role of perceived social support between them.@*Methods@#From April 2018 to January 2019, we invited 456 breast cancer patients hospitalized in the Department of Breast surgery in Qilu Hospital of Shandong University in Jinan to participate in the study and to finish a questionnaire survey which including the general information questionnaire, Chinese version of the Fear of Progression Questionnaire-Short Form, The Connor-Davidson Resilience Scale and Perceived Social Support Scale.@*Results@#The average score of fear of cancer recurrence in breast cancer patients was (41.5±7.7), and 85.99% (313/364) of the patients′ score was clinically significant (total score ≥ 34). Resilience could negatively predict the fear of cancer recurrence (β=-0.240 P < 0.01). Perceived social support is the moderation between resilience and fear of cancer recurrence (β=-0.179, P<0.01).@*Conclusions@#The level of resilience could affect the level of fear of cancer recurrence in breast cancer patients, and the increase in the level of perceived social support could enhance the effect of resilience on the fear of cancer recurrence, thus further reducing the level of patient′s fear of recurrence.
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Objective To describe and analyze the epidemiological characteristics of malaria in Dalian City, so as to provide the evidence for adjusting and formulating malaria control strategy and measures, being in accordance with the practical situation in Dalian City. Methods The data of malaria cases in Dalian City from 2005 to 2016 were collected from China Diseases Surveillance Information Reporting Management System (DSIRMS), to describe and analyze the epidemiologic characteristics of malaria in Dalian City. Results A total of 143 malaria cases were reported in Dalian from 2005 to 2016, including 115 laboratory diagnosed cases, 27 clinically diagnosed cases, and 1 suspected diagnosed case. Among the 115 laboratory diagnosed patients, 65 patients were infected with Plasmodium falciparum, 19 were infected with P. vivax, and 15 had mixed infection, 4 were infected with P. ovale, 3 were infected with P. malariae, and 9 were unclassified. All the cases were imported, 127 were imported from Africa, accounting for 88.81%, mainly were imported from Equatorial Guinea, Liberia, Ghana and Nigeria. Most of the cases were imported from May to October, accounting for 58.74% (84/143), and the imported cases emerged a small peak in August. The ratio of males to females was 10∶1, and the median age was 42 years. Among the total cases, fishermen, migrant workers, and work-man accounted for 55.24% (79/143). Seventy-five patients lived in rural districts, and 68 patients lived in urban districts. The median interval from backing to China to disease onset was 8 days. The proportion of disease onset within one month after backing to China was 76.27% (90/118). The median interval from disease onset to diagnosis was 4 days, and the longest interval was 71 days. Totally 141 patients were cured and 2 died. Conclusion In order to avoid malaria death, we should strengthen the malaria prevention and control, especially in rural districts, enhance the training for professionals in the county health facilities, and the surveillance and health education for those who are returned from malaria-endemic areas.
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Objective To describe and analyze the epidemiological characteristics of malaria in Dalian City, so as to provide the evidence for adjusting and formulating malaria control strategy and measures, being in accordance with the practical situation in Dalian City. Methods The data of malaria cases in Dalian City from 2005 to 2016 were collected from China Diseases Surveillance Information Reporting Management System (DSIRMS), to describe and analyze the epidemiologic characteristics of malaria in Dalian City. Results A total of 143 malaria cases were reported in Dalian from 2005 to 2016, including 115 laboratory diagnosed cases, 27 clinically diagnosed cases, and 1 suspected diagnosed case. Among the 115 laboratory diagnosed patients, 65 patients were infected with Plasmodium falciparum, 19 were infected with P. vivax, and 15 had mixed infection, 4 were infected with P. ovale, 3 were infected with P. malariae, and 9 were unclassified. All the cases were imported, 127 were imported from Africa, accounting for 88.81%, mainly were imported from Equatorial Guinea, Liberia, Ghana and Nigeria. Most of the cases were imported from May to October, accounting for 58.74% (84/143), and the imported cases emerged a small peak in August. The ratio of males to females was 10∶1, and the median age was 42 years. Among the total cases, fishermen, migrant workers, and work-man accounted for 55.24% (79/143). Seventy-five patients lived in rural districts, and 68 patients lived in urban districts. The median interval from backing to China to disease onset was 8 days. The proportion of disease onset within one month after backing to China was 76.27% (90/118). The median interval from disease onset to diagnosis was 4 days, and the longest interval was 71 days. Totally 141 patients were cured and 2 died. Conclusion In order to avoid malaria death, we should strengthen the malaria prevention and control, especially in rural districts, enhance the training for professionals in the county health facilities, and the surveillance and health education for those who are returned from malaria-endemic areas.
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Objective To investigate the psychological pressure levels of pregnant women in late pregnancy and to analyze the influencing factors. Provide the basis for the intervention measures. Methods Totally 160 pregnant women in late pregnancy who took part in the antenatal examination were recruited and investigated using Pregnancy Pressure Scale (PPS), Pittsburgh Sleep Quality Index (PSQI), and demographic questionnaire. Results Total score of PPS was (53.06 ± 10.24) points. In order to protect the health and safety of the fetus in pregnant women caused by maternal psychological stress score ranked first in three pressure source bit highest score of (16.46 ± 5.16) points. Total score of PSQI was (7.51± 2.89) points. Compared with the different dimensions of sleep quality, the two dimensions of sleep time and falling asleep time were negatively correlated with pregnancy stress, and the rest were positively correlated. Age, pregnancy, parity, plan the actual sleep time, sleep disorders will be planned to as independent variables. In the late pregnant women psychological pressure as the dependent variable, multiple linear stepwise regression analysis, found that there are 3 variables into the regression equation: parity, pregnancy in plan, sleep disorders (P＜0.05). Conclusions Pregnant women have greater psychological pressure in late pregnancy, influenced by the conception, planning pregnancy, sleep disorders and other factors. Nursing staff should take care and guidance for the specific situation, so as to reduce the pregnancy pressure of pregnant women in late pregnancy, and better help them successfully pass the gestation period and delivery period.
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Objective@#To explore the turnover intention of nurses in Quzhou and its influential factors.@*Methods@#From July to August in 2017 cross-sectional study and self-filled questionnaire are used to investigate 980 nurses from 7 hospitals in Quzhou, including two third-level hospitals and five second-level ones. T-test, F-test, Pearson and linear regression are used in data with the method of statistical analysis.@*Results@#The total score of turnover intention of nurses was (14.95±3.17) points, and the index value was 62.27%, of which the turnover intention was above 78%. The analysis of Single factor showed that age (F=4.895) , Department (F=2.971) , title, nursing age (F=5.863) , self-assessment of physical conditions (F=4.092) were closely related to nurses’ turnover intention(P<0.05). According to Person’s correlation analysis, there are positive correlations between turnover intention and source of stressor, and moral distress (P<0.05) . Multiple linear regression showed that the nurses’ turnover intention was age, Department, health selfevaluation, stressor and moral distress.@*Conclusion@#The turnover intention of nurses is high, which is related to age, Department, self-evaluation of health, stressor and moral distress.